TRACES pilot pharmacokinetic study

This dataset summarizes raw data used to build the pharmacokinetic model. Patients were included if they were undergoing haemorrhagic cesarean section (blood loss > 800 mL) and receiving a single i.v dose of TA (0.5, 1 or 2 g over 1 minute). Non-inclusion criteria used were presented in the TRACES pilot study protocol.[1] The blood TDM samples were obtained from our patients at T0 (inclusion time, when bleeding ≥ 800 mL is diagnosed), T1 (at the end of injection), T15, T30, T60, T120, T180, and T360 (defined as 15, 30, 60, 120, 180 and 360 min after the injection). The urinary samples were collected within 6 hours after treatment.




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