TAILS N-terminomic and proteomic datasets of healthy human dental pulp (Data In Brief - Supplement)

Supplementary Tables for Data In Brief Article: TAILS N-terminomic and proteomic datasets of healthy human dental pulp. Ulrich Eckhard1,2, Giada Marino 1,2, Simon R. Abbey1,2, Ian Matthew2, and Christopher M. Overall1,2,3* * 1 Centre for Blood Research, The Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada * 2 Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada * 3 Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. * *To whom correspondence should be addressed. Email: chris.overall@ubc.ca The Data described here provide the in depth proteomic assessment of the human dental pulp proteome and N-terminome [1]. A total of 9 human dental pulps were processed and analyzed by the positional proteomics technique TAILS (Terminal Amine Isotopic Labelling of Substrates) N-terminomics. 38 liquid chromatography tandem mass spectrometry (LC-MS/MS) datasets were collected and analyzed using four database search engines in combination with statistical downstream evaluation, to yield the by far largest proteomic and N-terminomic dataset of any dental tissue to date. The raw mass spectrometry data and the corresponding metadata have been deposited in ProteomeXchange with the PXD identifier ; supplementary tables described in this article are available via Mendeley Data (http://dx.doi.org/10.17632/555j3kk4sw.1). [1] U. Eckhard, G. Marino, S.R. Abbey, G. Tharmarajah, I. Matthew, C.M. Overall, The Human Dental Pulp Proteome and N-Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues, J. Proteome Res. 14 (2015) 3568–3582. doi:10.1021/acs.jproteome.5b00579.

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